Bioclinic Naturals CortAlign, 30 Tablets

Promotes relaxation temporarily and increases resistance to stress and anxiety
Provides adaptogenic protection against diverse stressors
Herbal formula, no glandular extracts
Standardized herbal ingredients provide 5% of withanolides (ashwagandha), 8.5% of honokiol (magnolia), and 2.1% of berberine (phellodendron)
Each tablet contains clinical dosages of botanicals
Suitable for vegetarians
Feature Summary
CortAlign contains a unique variety of botanicals and nutrients shown to have a blunting effect on stress and anxiety, as well as normalizing cortisol secretion. Ashwagandha has a number of adaptogenic effects, including modulating GABA receptors, which is partly responsible for the significant reduction in anxiety and stress as shown in clinical trials. The KSM-66TM formulation of ashwagandha specifically has been shown to reduce serum cortisol levels by 27%, and improve markers of depression, stress, and anxiety compared to placebo.

The combination of magnolia and phellodendron (Relora®blend) helps reduce stress and anxiety, and has been shown to reduce salivary cortisol levels and perception of stress, improve other mood parameters, and prevent stress-related weight gain compared to placebo. L-theanine has also been shown to reduce anxiety in clinical trials, as well as both subjective stress and cortisol production in response to a stressful event.Phosphatidylserine plays a critical role in neuronal cell structure and function, and has been shown to blunt the stress response, improve mood, and normalize cortisol release.

Medicinal Ingredients: KSM-66 Ashwagandha™ Extract (Withania somnifera) (root) (5% Withanolides) 300 mg, Relora® Blend 250 mg, Magnolia Bark (Magnolia officinalis) (stem bark) (8.5% Honokiol) 68.75 mg, Phellodendron (Phellodendron amurense) (stem bark) (2.5% Berberine) 22.50 mg, L-Theanine 100 mg, Phosphatidylserine (Helianthus annuus) (seed) 25 mg.
Non-Medicinal Ingredients: Microcrystalline cellulose, dibasic calcium phosphate dihydrate, hydroxypropylcellulose, silica, croscarmellose sodium, stearic acid, coating (carbohydrate gum [cellulose], glycerin), vegetable grade magnesium stearate (lubricant).

Recommended Adult Dose: 2 tablets per day or as directed by a health care practitioner.