Bioclinic Naturals NEM 500 mg, 60 VCaps

Natural Eggshell Membrane (NEM®) is clinically proven to reduce joint pain and stiffness resulting from osteoarthritis
Clinically shown to reduce pain and stiffness resulting from moderate-intensity aerobic exercise
Pain, stiffness, and flexibility shown to improve within days of use
NEM provides multiple joint nutrients, including glucosamine, chondroitin, and collagen type I
One vegetarian capsule of NEM per day is the clinically proven dose
Feature Summary
Multiple clinical trials have shown that NEM reduces joint pain and stiffness associated with osteoarthritis, and reduces joint pain and stiffness caused by moderate-intensity aerobic exercise. NEM is comprised of (shell-free) eggshell membranes, a natural source of the glycosaminoglycans found in cartilage, including dermatan sulfate and chondroitin sulfate, hexosamines such as glucosamine, as well as hyaluronic acid and collagen type I. In vitro and in vivo trials indicate that NEM has multiple mechanisms of action, including the inhibition of several proinflammatory cytokines associated with joint inflammation, such as interleukin-1 beta (IL-1β) and tumour necrosis factor-alpha (TNF-α).

In a randomized, double-blind, placebo-controlled trial, NEM was shown to rapidly reduce pain, stiffness, and discomfort following exercise in healthy postmenopausal women. It was also shown to reduce urinary levels of C-terminal cross-linked telopeptide of type II collagen (CTX-II), a biomarker for cartilage degradation, both in healthy people and those with joint disease.4 In addition, controlled clinical trials have shown a reduction in joint pain and stiffness in individuals with knee osteoarthritis within 10 days of use. Open-label trials have shown persistent improvements in pain and flexibility for multiple joint and connective tissue disorders within one week.

Medicinal Ingredients: NEM® Natural Eggshell Membrane (Gallus gallus) (eggshell)    500 mg
Non-Medicinal Ingredients: Vegetarian capsule (carbohydrate gum, purified water, silica), dibasic calcium phosphate dihydrate, vegetable grade magnesium stearate (lubricant).

Recommended Adult Dose: 1 capsule per day or as directed by a health care practitioner. Consult a health care practitioner for use beyond 8 weeks.