Bioclinic Naturals SAMe · 200 mg, 30 Delayed-Release Tablets

Key factor in several biological pathways, including methylation reactions, glutathione formation, and glutathione S-transferase activity1
Contains 200 mg of high quality SAMe, produced using a fermentation process that yields higher active ingredients over synthetic variations
Enteric coated to ensure a biologically active product
Suitable for vegetarians
Feature Summary
S-adenosyl-L-methionine (SAMe) has several critical physiological functions and is the common thread between three key metabolic pathways.* SAMe is well recognized as a unique methyl donor for more than 100 biological reactions, including DNA methylation. It also links methylation to polyamine synthesis (necessary for cell survival and growth) and trans-sulfuration, which is responsible for cysteine production, the rate-limiting factor in glutathione synthesis. Its unique positioning within these intersecting pathways explains its role as a regulator of redox status, cellular metabolism, proliferation, and normal apoptosis.

SAMe helps support joint health and emotional well-being.* It is required for the synthesis of serotonin, norepinephrine, and dopamine, which helps in the maintenance of emotional health. SAMe also helps maintain healthy sexual function.*11 Through the support of healthy cartilage, glutathione production, DNA methylation, and gene expression, SAMe helps maintain joint health.*13,14 Additionally, research suggests it may contribute to the support of endothelial function and neurological health.

Suggested Usage: Take on an empty stomach: 
For mood balance: 1–4 tablets 2 times per day or as directed by a health care professional. 
For joint support: 1–3 tablets 2 times per day or as directed by a health care professional. Do not exceed a total of 8 tablets per day. SAMe must be taken for a minimum of 2 weeks, at which time effects should be observed.