Offers balance of key fat-soluble vitamins, A, D, and K, critical to bone health
Contains vitamin K2 (MK-7), the most bioactive and long-lasting form
K2 (MK-7) helps increase vertebral bone mineral density among postmenopausal women
Provides vitamin D3 effective in maintaining blood levels of 25-OH vitamin D23
Optimal form of vitamin A, palmitate
Suitable for vegetarians
Feature Summary
Vitamin K2, D3 &A provides clinically relevant doses of the three fat-soluble vitamins essential to optimal bone health. Although needed for cardiovascular health, blood sugar regulation, immune function, and inflammation control, vitamins A, D, and K2 have complementary physiological bone-related functions, such as modulating gene expression in osteoblasts and carboxylating osteocalcin, an enzyme needed for bone formation.1 This is exemplified by a reduction in undercarboxylated osteocalcin and an increase in bone mineral density (BMD) in postmenopausal women when vitamin K is added to vitamin D supplementation.2
Vitamin D has diverse and significant functions in multiple body systems, and widespread deficiency magnifies these crucial roles.3,4 Supplementation is associated with a well-established reduction in osteoporotic fracture.5 Correcting a vitamin D deficiency is critical when supplementing with vitamin A, as vitamin A appears to promote bone health if vitamin D levels are adequate.6,7,8 Vitamin K is now recognized as being necessary not only for coagulation, but for the carboxylation of enzymes critical for both bone and blood vessel health.9-13 Indeed, meta-analysis has shown improvement in vertebral BMD and reduction in fracture among post-menopausal women with osteoporosis, while controlled trial data shows a reduction in the age-related decline in BMD among healthy postmenopausal women.14,15 The naturally derived MK-7 form in Vitamin K2, D3 &A has a longer half-life than any other form.
Medicinal Ingredients: Vitamin A (Palmitate) 500 IU (151 mcg RAE), Vitamin D3 (Cholecalciferol) 1000 IU (25 mcg), Vitamin K2 (Menaquinone-7) (MK-7) (natto bean) 50 mcg
Non-Medicinal Ingredients: Medium chain triglycerides, organic flaxseed oil, natural vitamin E (non-GMO sunflower oil), natural vanilla flavour.
1 serving (0.25 ml) per day or as directed by a health care practitioner.